منابع مشابه
Targeted Nanoparticles for Cancer Therapy
The World Health Organization (WHO) estimates that 84 million people will die of cancer between 2005-2015 [1]. According using the WHO mortality database it has been estimated the total number of cancer deaths in the European Union (EU) and in 2012 is predicted to be 1283101, of which 717398 men and 565703 women [2]. The most common types of cancer that will be diagnosed are lung (C33-C34), int...
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Glioblastoma (GBM) is the most aggressive primary malignant brain cancer that invariably results in a dismal prognosis. Chemotherapy and radiotherapy have not been completely effective as standard treatment options for patients due to recurrent disease. We and others have therefore developed molecular strategies to specifically target interleukin 13 receptor alpha 2 (IL13RA2), a GBM restricted ...
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The phase 1 clinical trial of systemic Targeted Alpha Therapy for metastatic melanoma has shown that solid tumours can be regressed by alpha radiation. However, patient blood vessels and lymphocytes inevitably received a background radiation from non-targeted alpha decays in the blood circulation. To determine the toxicity of alpha particle to normal tissue capillaries and peripheral blood lymp...
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ژورنال
عنوان ژورنال: Nanomaterials
سال: 2020
ISSN: 2079-4991
DOI: 10.3390/nano10071366